Lorinda’s masters research focused on the use of flow chemistry for the development of synthetic routes to the antidepressants bupropion and fluoxetine, and the insecticide amitraz. In the case of the bupropion, Lorinda together with Nicole Neyt co-developed a fully automated green synthesis of the anti-depressant. Lorinda’s current research continues to focus on the development of flow process routes to pharmaceuticals, in addition she is also studying the utility of 3D printing as a rapid prototyping tool for the development of new flow reactors with a focus on reactors that can process slurries.

Dissertation

Utilization Of Flow Chemistry For The Syntheses Of Bupropion, Fluoxetine And Amitraz.

Conferences

  1. 2022 RSC twitter poster conference, Continuous microflow synthesis of Bupropion Hydrochloride: A green approach Second place poster prize engineering catagory
  2. 47th IUPAC World Chemistry Congress, Paris, France, July, 2019: A green approach to synthesize Bupropion under flow conditions, L.T van Wyk, N.C. Neyt, D.L. Riley
  3. SAAWK Conference, Pretoria, South Africa, November 2017: Aaneenlopende vloei sintese van ‘n selektiwe serotonien heropname inhibeerdeer (SSHI), fluoksetein, L.T. van Wyk, I. Strydom, D.L. Riley – Poster Prize